Mouse FFPE · Research use
Mouse tissue
FFPE tissue blocks and custom slides from immunodeficient and immunocompetent mouse strains, for humanized-model, immuno-oncology, and oncology studies. We can also collect and block tissue from your own animals.
Core strains
NSG-MHC I/II DKO
Immunodeficient · humanized models
C57BL/6
Immunocompetent · inbred
BALB/c
Immunocompetent · inbred
Other strains on request
Core strains
Tissue for humanized, syngeneic, and knockout studies
FFPE tissue blocks and custom slides from these strains, ready to order.
Immunodeficient · humanized models
NSG-MHC I/II DKO
Male and Female available
NSG mice lacking mouse MHC class I and II. Used as hosts for PBMC-humanized studies, where the missing mouse MHC reduces graft-versus-host disease and extends the study window.
Used for
- Control tissue for humanized-mouse immuno-oncology studies
- Checking that anti-human antibodies don't stain mouse tissue
- Baseline histology of the host strain
Immunocompetent · inbred
C57BL/6
The most widely used inbred strain and the background for most knockout and transgenic lines. Host for syngeneic tumours such as MC38, B16, and LLC.
Used for
- Wild-type controls for knockout and transgenic studies
- Normal tissue for syngeneic oncology and immunology studies
- IHC and multiplex IF assay development on mouse tissue
Immunocompetent · inbred
BALB/c
Widely used inbred strain in immunology and antibody work. Host for syngeneic tumours such as CT26, 4T1, and EMT6.
Used for
- Normal tissue for syngeneic tumour studies
- Immunology and vaccine study controls
- IHC and multiplex IF assay development on mouse tissue
Standard organ panel
Availability varies by strain and sex. Tell us the organs you need in your enquiry.
- Brain
- Heart
- Lung
- Liver
- Kidney
- Spleen
- Thymus
- Lymph node
- Stomach
- Duodenum
- Jejunum
- Ileum
- Cecum
- Colon
- Rectum
- Pancreas
- Skin
- Skeletal muscle
- Bone / bone marrow
- Reproductive organs
What you can order
FFPE blocks
Single-organ blocks or multi-organ blocks from one animal.
Custom FFPE slides
Unstained sections cut to your thickness and slide type, or stained with H&E, IHC, or multiplex IF.
From our lab
Mouse stains we run
Special stains and IHC on mouse FFPE tissue, from normal and disease models.
Trichrome
Normal lung, 5-week-old mouse
Trichrome
Bleomycin-induced fibrotic lung
IHC
Spleen
IHC
Spleen, lymphoid follicles
IHC
Duodenum
IHC
Lymphoid tissue
Why it matters
Built for mouse studies
Strain-matched mouse tissue for the work that surrounds an in vivo study.
Antibody specificity
Show that anti-human antibodies used in humanized-mouse studies don't stain mouse tissue.
Baseline histology
Know what normal looks like in each strain before reading study tissue.
Assay development
Set up and validate IHC and multiplex IF panels before study samples arrive.
Study controls
Strain-matched normal tissue for syngeneic, xenograft, and humanized models.
On request
Other strains
Blocks and slides from other strains are available on request.
Immunodeficient and humanized
- NSG
- NSG-SGM3
- NOD-SCID
- NOG
- NRG
- Nude (athymic)
Inbred and outbred
- FVB/N
- C3H
- DBA/2
- 129
- CD-1
- Swiss Webster
Disease models
- NOD (type 1 diabetes)
- MRL/lpr (lupus)
- SJL (EAE)
- DBA/1 (arthritis)
Genetically modified
- Knockout lines
- Transgenic lines
- Humanized knock-in lines
Custom collection
Your animals, our FFPE blocks.
We collect tissue from animals you provide and turn it into FFPE blocks and slides, to your organ list and study design.
- 1
Plan the collection
Agree the organ list, fixation, and block or slide format for your study.
- 2
Arrange the animals
We confirm logistics for your animals or tissues and timing with you.
- 3
Collection and fixation
Tissues are collected to your organ list and fixed in formalin.
- 4
Blocks and slides back
We process and embed to FFPE, then return blocks, slides, or stained sections.